AstraZeneca
Job Responsibilities
1. End-to-End Management of CAR-T R&D Projects
• Support the initiation and evaluation of CAR-T R&D projects, including defining project objectives, milestones, and development plans, and monitoring key deliverables.
• Assist in tracking project progress and conducting variance analysis; coordinate cross-functional resources (Discovery, PD/CMC and Clinical teams etc.) to resolve issues and ensure projects are delivered on schedule.
• Support project budget management and ensure rational and efficient use of R&D investment.
2. Cross-Functional Collaboration and Resource Integration
• Coordinate closely with R&D, Clinical, PD/CMC Management, Regulatory Affairs, Quality, and other internal teams to ensure information alignment and goal consistency.
• Interface with external partners and CROs, managing technology transfer, data delivery, and compliance review activities.
3. Regulatory Compliance and Risk Management
• Maintain solid knowledge of CAR-T–related regulations; identify project risks, develop mitigation strategies, and provide regular updates to management.
4. Technical and Scientific Support
• Participate in technical discussions related to CAR-T products; understand critical quality attributes (CQAs) and provide directional support for process development and quality studies.
• Monitor industry trends and scientific advancements to support pipeline strategy and portfolio planning.
5. Documentation and Knowledge Management
• Ensure project documentation complies with relevant regulatory and internal standards; maintain timely archiving and version control.
6. Other tasks assigned by management
Qualifications
1. Education & Academic Background
• Master’s degree, or Ph.D degree in Biotechnology, Biopharmaceutical Sciences, Medicine, Immunology, Bioengineering, or related fields preferred.
• Background in molecular biology, cell biology, immunology or virology is a plus.
2. Industry Experience
• At least 5 years of R&D project management experience in the pharmaceutical or biotech industry;
• Minimum 2 years of end-to-end project management experience in CAR-T, cell therapy, or monoclonal antibody (mAb) programs.
• Proven experience in successfully advancing CAR-T or mAb products into Phase I or Phase II clinical trials is highly preferred.
• Familiar with the full development lifecycle of cell therapies; knowledge of viral vector manufacturing and T-cell expansion technologies is a plus.
3. Core Competencies
• Strong understanding of domestic and international pharmaceutical regulations.
• Excellent cross-functional communication and coordination skills, with the ability to drive collaboration among technical, clinical, and manufacturing teams.
• Excellent written and reading English skills; fluent spoken English is a plus.
• Strong passion for the cell therapy field, with an innovative mindset, resilience under pressure, and strong problem-solving ability in a fast-paced R&D environment.
• Strong logical thinking, data analysis capability, and scientific rigor.
Date Posted
01-7月-2026
Closing Date
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.