Xaira Therapeutics
$101k – $126k
About Xaira Therapeutics
Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.
About the Role
We are seeking a Scientist to join our Immunogenicity team within Biology & Pharmacology to lead and execute immunogenicity risk assessment for de novo protein therapeutics. This role is central to our Immunogenicity Risk Assessment and Management framework, encompassing pre-clinical immunogenicity characterization, ADA assay development, and risk-tiering of novel biologic formats including VHH antibodies, minibinders, and T cell engager (TCE) bispecific antibodies. You will operate at the interface of translational science and assay development, partnering closely with discovery biology, process development, and clinical teams to ensure immunogenic risk is identified and managed across the development pipeline.
About You
The successful candidate is a hands-on immunogenicity scientist with a strong grasp of antibody biology, T and B cell immunology, and bioanalytical assay development. At this level, you independently design and execute experiments of significant scope and complexity — establishing experimental strategy, selecting appropriate methods, drawing conclusions, and defining next steps with minimal supervision. You are comfortable evaluating variable factors in complex datasets, exercising scientific judgment to interpret relationships and solve problems within defined frameworks, and knowing when to seek guidance on broader implications.
You actively collaborate, share knowledge, and support peers across the immunogenicity and broader translational sciences team. You are comfortable contributing to cross-functional updates and have a track record of identifying opportunities for improvement and implementing changes within your personal scope. You thrive in fast-paced environments and bring a rigorous yet pragmatic approach to assay design, data interpretation, and risk communication. You are comfortable leveraging AI tools to accelerate experimental design, synthesize complex datasets, and surface actionable insights.
Key Responsibilities
Qualifications
Compensation
We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity. The base pay range for this position is expected to be $101,000 - $126,000 annually; however, the base pay offered will vary depending on the market, job-related knowledge, skills and capabilities, and experience.
Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.
TO ALL RECRUITMENT AGENCIES: Xaira Therapeutics does not accept agency resumes. Please do not forward resumes to our jobs alias or employees. Xaira Therapeutics is not responsible for any fees related to unsolicited resumes.